Semax
A Russian developed peptide with the stress hormone part deliberately cut away.
| Property | Value |
|---|---|
| Type | Peptide, 7 amino acids |
| Origin | Fragment of ACTH with a tail added |
| Research field | Attention, memory, protection of nerve cells |
| Research status | Clinically used in Russia, not registered elsewhere |
| Form | Freeze dried powder |
What it is
ACTH is the hormone prompting the adrenal gland to make cortisol. Semax is a short stretch of it, extended with a three amino acid tail for stability. The hormonal action is gone.
How it works
The mechanism named most often is BDNF, a protein nerve cells use to maintain connections and build new ones. Effects on dopamine and serotonin are also described.
What the research shows
In Russia it is registered and clinically used. A large part of the literature was published in Russian and not always translated, so a search in English databases returns less than exists, and independent replication is often missing.
Research status
Registered in Russia, a research compound elsewhere.
Practical
An N-acetyl variant of Semax also exists, with a cap at the start of the chain keeping it intact longer. Otherwise it is the same molecule.
This site is made by the team behind Apex Bio Research, a Dutch supplier of research peptides with a certificate of analysis per batch.
Visit the shopThis site explains what the scientific literature says about peptides. It is not medical advice and not a set of instructions. The substances discussed here are research compounds: they are not approved for use in humans or animals. If you have a health question, see a doctor.